define glucagon

What defines glucagon product attributes in peptide composition?

Abstract: Glucagon, a 29-amino-acid peptide, is defined by its specific sequence (HSQGTFTSDYSKYLDSRRAQDFVQWLMNT) and purity (>98% by HPLC). In the peptide market, glucagon products are differentiated by brand (e.g., Novo Nordisk vs. generic), synthesis technology (solid-phase vs. recombinant), and regulatory certifications (FDA, GMP). Key product attributes include stability (lyophilized vs. liquid), bioactivity (≥10,000 IU/mg), and logistics (cold-chain at -20°C). Current industry trends show a 12% CAGR for glucagon analogs, driven by diabetes and obesity applications. Selection criteria prioritize purity, endotoxin levels (<1 EU/mg), and supplier GMP audits.